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PPI Frequently Asked Questions
Why might my PPI medication not be working for heartburn?
PPIs may not work if you have the wrong diagnosis, take them inconsistently, or need dosage adjustments. Some people also develop tolerance over time.
When should I consider stopping my PPI medication?
You should consider stopping PPIs when symptoms improve, after 4-8 weeks for GERD, or if experiencing side effects like nutrient deficiencies or increased infection risk.
How do proton pump inhibitors affect the body long-term?
Long-term PPI use may reduce nutrient absorption (especially magnesium, calcium, B12), alter gut microbiome, and potentially increase fracture risk. Always consult your doctor about duration.